For People New to Microdosing
What is Microdosing?
Microdosing involves consuming very small, precisely measured amounts of psychedelic substances, commonly psilocybin-containing mushrooms. These mushrooms contain various bioactive compounds, including psilocybin, psilocin, baeocystin, norbaeocystin, and aeruginascin, which may work together to produce beneficial effects (Cameron et al., 2020). Additionally, trace amounts of β-carbolines, such as harmane and harmine, have been detected in different Psilocybe species and may contribute positively to their activity (Blei et al., 2019).
Although psilocybin is the primary psychoactive component in these fungi, other tryptamines present in whole mushrooms may also contribute to their overall therapeutic potential. The goal of microdosing is to enhance mood, focus, creativity, and emotional well-being while maintaining full functionality.
What Are the Potential Benefits of Microdosing?
Many individuals who microdose report improved concentration, heightened productivity, and increased emotional stability. Users often experience enhanced creativity, allowing them to approach challenges with fresh perspectives. Research supports these claims, showing associations between microdosing and increased mood stability (26.6%), enhanced focus (14.8%), and greater creativity (12.9%) (Anderson et al., 2019; Fadiman & Korb, 2019).
Is Microdosing Legal?
The legal status of microdosing varies by region. While some locations have decriminalized or approved the use of psychedelics for therapeutic purposes, others continue to prohibit them. It is essential to research and understand the laws in your area before beginning a microdosing regimen (Carhart-Harris & Goodwin, 2017).
How Does Microdosing Work?
Psilocybin, the primary psychoactive component in certain mushrooms, is converted into psilocin in the body. Psilocin interacts with serotonin receptors, particularly the 5-HT2A receptor, which plays a role in mood regulation, cognition, and perception. Studies suggest that even at low doses, psilocybin may promote neural plasticity, allowing the brain to form new connections that support creativity and emotional resilience (Cameron et al., 2020; Shao et al., 2021; Carhart-Harris et al., 2018).
How Can I Ensure a Positive Microdosing Experience?
Microdosing is most beneficial when approached with intention. Users can maximize its positive effects by maintaining a structured routine, journaling their experiences, and incorporating other wellness practices such as meditation, exercise, and creative activities (Anderson et al., 2019; Fadiman, 2011). Many individuals report that microdosing fosters personal growth and enhances their overall well-being.
Will Microdosing Make Me ‘High’?
No, microdosing involves taking such a small amount that users do not experience intense perceptual changes. Instead, they report feeling more focused, emotionally balanced, and creatively inspired (Szigeti et al., 2021; Johnstad, 2018).
How Do I Find the Right Dose?
The optimal microdose typically ranges between 1/10th and 1/20th of a full psychedelic dose. Starting with a low amount helps ensure a positive experience, and gradual adjustments can be made if necessary. Users often find that subtle shifts in mood, energy, and creativity indicate they have reached the right dose (Szigeti et al., 2021; Fadiman, 2011).
For Experienced Microdosers
How Do I Know If My Microdosing Routine is Effective?
Tracking mood, focus, creativity, and overall well-being over time is an effective way to gauge the success of a microdosing routine. Many users find that consistency and mindfulness lead to noticeable improvements in their daily lives (Polito & Stevenson, 2019; Carhart-Harris & Goodwin, 2017).
Can Microdosing Enhance Creativity?
Many users report increased creativity, with artists, writers, and professionals citing improved problem-solving abilities and fresh insights. Scientific research suggests that microdosing may support creative thinking and innovation. Prochazkova et al. (2018) found that individuals who microdosed exhibited enhanced creative problem-solving abilities and increased divergent thinking, which are key components of creativity.
Can Microdosing Be Combined With Other Practices?
Microdosing pairs well with mindfulness, meditation, journaling, or therapy. These complementary practices can help integrate its subtle effects into a broader personal growth and wellness strategy, enhancing its positive impact (Anderson et al., 2019; Fadiman & Korb, 2019).
How Can I Maintain the Benefits of Microdosing Over Time?
To sustain long-term benefits, users can maintain consistency in their microdosing practice while incorporating mindfulness and other positive habits to reinforce their well-being. Many people report that microdosing fosters ongoing growth, positivity, and well-being (Johnstad, 2018; Cameron et al., 2020).
Is Microdosing Safe for Long-Term Use?
Many individuals who microdose report ongoing benefits, including enhanced mood, increased creativity, and improved focus. Research indicates that microdosers tend to experience lower levels of anxiety and depression compared to those who do not microdose (Rootman et al., 2021). Although scientific studies on long-term effects are still developing, microdosing is widely regarded as a positive and beneficial practice when done mindfully and with regular breaks to maintain effectiveness.
Understanding Mushroom Potency and Gram-Based Dosing
Why does mushroom potency vary so much?
Mushroom potency is influenced by several factors, including species, cultivar, growing conditions, and drying methods. For example, Psilocybe cubensis is considered a standard species for dosing, but varieties like P. azurescens or P. cyanescens can be several times more potent (Beug & Bigwood, 1982; Guzmán et al., 2000). Even within the same species, different batches may contain varying levels of psilocybin, psilocin, and other bioactive compounds, meaning one person’s 2g experience might feel like another person’s 1.5g or 3g (Stijve & Kuyper, 1985).
How do drying and storage affect potency?
Drying and storage conditions play a crucial role in preserving mushroom potency. Older or improperly stored mushrooms may degrade over time, leading to weaker effects (Gartz, 1994). To maintain potency, mushrooms should be dried properly and stored in airtight containers away from heat and light.
How should I approach dosing given these variations?
Because of these potency variations, it is always best to start on the lower end of a dose range and adjust cautiously rather than relying on exact gram measurements alone (Stamets, 1996).
Higher Doses
Low Dosing (0.3g – 1g, dried mushrooms)
What is a low dose?
Low dosing involves consuming slightly more than a microdose but staying below the threshold of a full psychedelic experience. While the effects remain mild, they are often noticeable, including enhanced sensory perception, subtle shifts in thought patterns, and greater emotional openness. Many individuals report increased creativity, heightened introspection, and an improved ability to engage with activities such as meditation, journaling, or artistic projects (Hutcheson et al., 2022).
What are the common effects of a low dose?
At the lower end of this range, effects might include a general sense of clarity and connection. Doses closer to 1g may bring slight visual enhancements, such as richer colors or mild pattern movement. These effects can vary significantly depending on factors like species, cultivars, and growing conditions, which influence the potency of psychoactive compounds like psilocybin and psilocin (Passie et al., 2002).
Can I function normally while low dosing?
It depends, low doses are generally manageable in everyday settings, but they require intention, as emotions and thought patterns may feel more pronounced.
Medium Dosing (1g – 2.5g, dried mushrooms)
What is a medium dose?
A medium dose offers a more immersive psychedelic experience, typically marked by noticeable perceptual changes, time dilation, and introspective thought loops. Users often report intensified emotions, profound self-reflection, and an increased sense of interconnectedness with nature or their surroundings. While the experience is not overwhelming for most, it can be transformative and thought-provoking, making it a popular range for personal insight and therapeutic self-exploration (Griffiths et al., 2006).
What are the common effects of a medium dose?
At the lower end (around 1g), effects may include mild euphoria, a dreamy state of mind, and enhanced appreciation for music, nature, or art. Higher doses in this range (2g – 2.5g) can introduce visual distortions, including shifting textures, enhanced patterns, and mild synesthesia (blending of senses).
Why does potency vary between medium doses?
Psilocybin content varies by species and growth conditions, meaning a 2g dose of one variety may be much stronger than the same dose of another (Beug & Bigwood, 1982). Setting and intention are key at this level, as experiences can range from enlightening and insightful to emotionally intense.
Macrodosing (Clinical & Therapeutic Use) (2.5g – 5g+, dried mushrooms)
What is macrodosing?
Macrodosing refers to taking larger amounts of psilocybin mushrooms, leading to profound, often life-changing experiences. Clinical research and indigenous traditions suggest that high doses (3g and beyond) can facilitate extensive emotional processing, mystical states, and a sense of ego dissolution, where one’s sense of self temporarily fades, replaced by a feeling of unity or transcendence (Griffiths et al., 2006).
What happens during a macrodose?
Doses around 3g-4g can produce vivid visuals, powerful introspection, and significant emotional shifts. At 5g or more (“heroic doses”), users commonly report full ego dissolution, time distortion, and an overwhelming sense of connection to the universe or spiritual insights.
Is macrodosing suitable for everyone?
These effects can be transformative but also challenging, requiring proper preparation, integration, and often the guidance of a trained facilitator (Johnson et al., 2008).
How does macrodosing impact mental health?
The potency of macrodosing varies widely based on species (e.g., Psilocybe cubensis vs. P. azurescens), cultivar, individual tolerance, and even storage conditions. This is why experienced practitioners emphasize careful preparation, responsible use, and appropriate set and setting. In clinical trials, psilocybin-assisted therapy has shown promising results for treating depression, PTSD, addiction, and existential distress, often with just one or two well-facilitated sessions (Ross et al., 2016).
Further Reading
Can Microdosing Mushrooms Reduce Anxiety and Depression?
Medical News Today (2021).
Read the article
Microdosing Psilocybin Mushrooms May Improve Mental Health and Mood
Healthline (2021).
Read the article
Psychedelic Mushroom Microdoses Can Improve Mood, Mental Health
UBC Okanagan News (2022).
Read the article
The Popularity of Microdosing of Psychedelics: What Does the Science Say?
Harvard Health Blog (2022).
Read the article
Americans’ Interest in Microdosing Psychedelics Is Growing
U.S. News & World Report (2024).
Read the article
If you’re ready to explore the potential of microdosing and want guidance tailored to your needs, book a consultation today. Together, we can create a safe, effective plan to help you achieve your goals.
References
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https://pubmed.ncbi.nlm.nih.gov/30604183/
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https://www.researchgate.net/publication/15998152_Psilocybin_and_psilocin_levels_in_twenty_species_from_seven_genera_of_wild_mushrooms_in_the_Pacific_Northwest_USA
- Blei, F., Dörner, S., Fricke, J., Baldeweg, F., & Hoffmeister, D. (2019). Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in “magic” mushrooms. Chemistry – A European Journal, 25(30), 7617–7624.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.201904363
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https://doi.org/10.1080/02791072.2020.1718250
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https://www.nature.com/articles/npp201784
- Fadiman, J. (2011). The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys. Park Street Press.
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https://www.tandfonline.com/doi/abs/10.1080/02791072.2019.1567969
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https://pubmed.ncbi.nlm.nih.gov/16826400/
- Hutcheson, B. S., Lucas, C. J., & Luckett, T. (2022). Microdosing with psilocybin mushrooms: A double-blind placebo-controlled study. Translational Psychiatry, 12(1), 1-9.
https://www.nature.com/articles/s41398-022-01821-5
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https://pubmed.ncbi.nlm.nih.gov/14578010/
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211023
- Prochazkova, R., Lippelt, D. P., Colzato, L. S., Kuchar, M., Sjoerds, Z., & Hommel, B. (2018). Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting. Psychopharmacology, 235(12), 3401-3413.
https://link.springer.com/article/10.1007/s00213-018-5049-7
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https://www.nature.com/articles/s41598-021-01811-4
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https://pubmed.ncbi.nlm.nih.gov/27909164/